Studying Atrial Fibrillation Terminated by Local Ablation

Atrial Flutter pic
Atrial Fibrillation

An experienced researcher specializing in atrial fibrillation, Dr. Sanjiv M. Narayan, professor of medicine at Stanford University, is responsible for developing innovative assessment tools for diagnosing heart arrhythmia conditions. Dr. Sanjiv M. Narayan’s research recently focused on the mechanisms of and relationship between localized ablation and persistent atrial fibrillation termination.

As part of a clinical trial, researchers hypothesized that local ablation sites where AF persistently terminates have certain indicators that can be analyzed through activation mapping techniques. To test this theory, they closely studied activation patterns that occurred solely in instances of AF termination via ablation.

After examining the results, the research team found patterns of either rotational or focal activity when mapping termination sites. Computer simulations also revealed rotational activation sequences, but the sequences were found to have increased sensitivity to activation timing, especially in areas where slow conduction was a factor. Based on these observations, the researchers stated that many currently used tools to map AF may not detect important regions, including sites of termination, and further studies should compare mapping approaches to guide ablation.


Acutus Medical Launches AcQMap Imaging and Mapping System

Acutus Medical pic
Acutus Medical

A professor of Medicine at Stanford University, Dr. Sanjiv M. Narayan is a well established atrial fibrillation (AF) researcher who has created technology-driven solutions for assessing complex heart arrhythmia conditions. Dr. Sanjiv M. Narayan’s foundational work has informed studies that apply novel technologies to map AF and find localized ablation targets.

In May 2018, Acutus Medical announced the launch of the high-resolution AcQMap imaging & mapping system, as well as a 3-D mapping catheter. Used together, these pieces of equipment generate real time ultrasound-enabled 3-D heart chamber images. Detecting and displaying charge-source and voltage-based maps, the AcQMap system is described as enabling physicians to better view “complex, irregular arrhythmias.”

With a clinical study of AcQMap having been launched, the potential for the FDA-approved system in enhancing AF retreatment ablation procedures is of intense interest. Acutus Medical also entered into a partnership with Stereotaxis in incorporating the latter firm’s magnetic navigation system within its AcQMap mapping and imaging system.